Seresto vs. Nexgard: Which Flea and Tick Treatment is Right for Your Dog?
Selecting the best flea and tick treatment for your dog is not an easy feat. You have to consider many factors, including effectiveness, preference, convenience, and health condition of your pet. Plus, the myriad of options available in the market makes it even more challenging.
In this blog, we’ll put two treatments, Seresto Collar and Nexgard Chewables, side by side and discuss their effectiveness. Whether you prefer long-term protection or a monthly treatment, this comparison guide will help you make an informed choice.
So, let’s get started!
Understanding the Treatments: Overview
In this segment, we’ll discuss the treatments to understand their effectiveness and then dive deeper into the differences and similarities.
Seresto Collar
Seresto Collar is an odorless and non-greasy collar designed to protect dogs against fleas and ticks. Featuring Flumethrin and Imidacloprid as the active ingredients, it kills and repels fleas and ticks on contact. Plus, it kills fleas that may transmit flea tapeworms.
Seresto Collar protects against American dog ticks, deer dog ticks, brown dog ticks, and lone star ticks. It also aids in the prevention of Lyme disease and other tick-borne diseases. Made using a unique polymer matrix technology, it facilitates a slow and steady release of active ingredients on the dog, protecting them for up to 8 months.
Nexgard Chewables
Nexgard Chewables is a beef-flavored oral Flea and Tick treatment formulated to protect dogs and puppies from 8 weeks of age, weighing at least 4 lbs, against fleas and ticks. These highly palatable chews feature Afoxolaner as the active ingredient and kill fleas before they can lay eggs and effectively prevent flea infestations.
The monthly chew treats and controls tick infestations caused by black-legged ticks, American dog ticks, lone star ticks, brown dog ticks, and long-horned ticks. Plus, it is indicated to prevent Lyme disease in dogs as a direct result of killing black-legged vector ticks.
Seresto vs. Nexgard: Side-by-Side Comparison
Let’s take a closer look at the differences and similarities of Nexgard Chewables and Seresto Collar with the following comparison table.

Which One to Select?
By now you can see that the effectiveness and protection coverage of Seresto Collar and Nexgard Chewable are almost identical. So which one to select?
The primary difference between these products is the mode of administration and duration of protection they provide. Nexgard chewables ensure monthly protection, while Seresto Collar protects for up to 8 months.
So, if you are looking for long-term protection, Seresto is your ideal pick. On the other hand, if your dog is not comfortable or allergic to collars, Nexgard is a solid option to keep them protected. However, it’s always best to consult your vet for expert advice. They will suggest the best-suited option depending on the condition and medical history of your dog.